Today I am going to share with you the effectiveness of the Gynura Procumbens plant on treating liver cancer. There were earlier articles on the use of the G. Procumbens to treat breast cancer, diabetes, high blood pressure and varicose vein in my previous postings.
According to a study carried out by Fithriyatun Nisa, Adam Hermawan, Retno Murwanti and Edy Meiyanto at the Cancer Chemoprevention Research Center, Faculty of Pharmacy, Universitas Gadjah Mada, Sekip Utara II, Yogyakarta 55281, Indonesia, states that,
This study explored the effect of G. procumbens leaves ethanolic extract on DMBA induced male rats liver. In this study, EGP was given a week before, during and after induction of DMBA. EGP treatment was intended to prevent metabolic activation of DMBA and also prevent initiatition and progression of liver cancer. Our present study showed that DMBA induced high proliferation compared to EGP treatment group. Treatment of EGP 300 mg/kgbw is significantly decreased proliferation of liver cells induced by DMBA. The results in similar to previous study 13 that reported treatment of EGP 300 mg/kgbw significantly (p<0.05) inhibited proliferation of mammary glands induced by DMBA. Antiproliferative activity of EGP is mediated by metabolic enzyme, CYP and GST [Full Text]
I am not a science person but I do understand that G. Procumbens is effective to inhibit cancer cell growth in a liver as the study below suggest:
Purpose: The leaves of Gynura procumbens (Lour.) Merr. has been traditionally used as anticancer. Ethanolic extract of G. procumbens leaves (EGP) showed cytotoxic activity and anticancer activity in animal cancer model. This study was conducted to observe antiproliferative effect using male rat’s liver cells induced by 7,12-dimethylbenz(a)antracene (DMBA). Methods: Forty days old Sprague Dawley male rats were divided into 4 groups, (1) 0.5 % CMC Na, (2) 20 mg/kg BW DMBA p.o ten
times in three weeks, (3) DMBA+300 mg/kg BW of EGP, and (4) DMBA+750 mg/kg BW of EGP. The extract was dissolved into 0.5 % CMC-and administered daily per oral one week before, during and terminated 1 week after the DMBA induction. After sixthteen week experiment, rat livers were sectioned and stained with Haematoxyllene and Eosin (H&E) and AgNOR. Results: Histopatology profile showed no primary liver tumor on DMBA group. mAgNOR value of DMBA+300 mg/kg BW EGP showed significant antiproliferative effect compared to DMBA group. Conclusion: Ethanolic
extract of G. procumbens leaves showed antiproliferative activity on male rats liver induced by DMBA. [Full Text]
Gynura procumbens
In layman term, the ethanolic element found on G. Procumbens leaves has the ability to inhibit the growth of cancer cells on male rats liver which is caused by DMBA. DMBA is a tumor initiator.
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I wish to conclude that Gynura procumbens does indeed have the properties to help fight cancer. I am not sure if a commercially available drug derived from the plant is available but planting the plant is actually quite straight forward. If you wish to plant it yourself, you may want to have a look at my previous post on the matter here and how to consume the leaves, over here.
Reference:
1. Advanced Pharmaceutical Bulletin, 2012, 2(1), 99-106
2. Korean J Physiol Pharmacol 2007 Aug; 11(4): 145-148